Package: PKPDsim
Type: Package
Title: Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations
Version: 1.5.0
Date: 2025-07-08
Authors@R: c(
        person("Ron", "Keizer", email = "ron@insight-rx.com", role = c("aut", "cre")),
        person("Jasmine", "Hughes", email = "jasmine@insight-rx.com", role = "aut"),
        person("Dominic", "Tong", email = "dominic@insight-rx.com", role = "aut"),
        person("Kara", "Woo", email = "kara@insight-rx.com", role = c("aut")),
        person("Jordan", "Brooks", email = "jordan.brooks@insight-rx.com", role = "aut"),
        person("InsightRX", role = c("cph", "fnd")))
Depends: R (>= 4.0.0)
Imports: Rcpp (>= 1.0.13), BH, data.table, stringr, MASS, randtoolbox,
        jsonlite, stats, parallel, magrittr
Suggests: httr, testthat (>= 3.0.0), knitr, rmarkdown
LinkingTo: BH, Rcpp (>= 1.0.13)
Description: Simulate dose regimens for pharmacokinetic-pharmacodynamic
        (PK-PD) models described by differential equation (DE) systems.
        Simulation using ADVAN-style analytical equations is also
        supported (Abuhelwa et al. (2015)
        <doi:10.1016/j.vascn.2015.03.004>).
License: MIT + file LICENSE
URL: https://github.com/InsightRX/PKPDsim,
        https://insightrx.github.io/PKPDsim/
Language: en-US
LazyData: TRUE
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Config/testthat/edition: 3
Config/Needs/website: tidyverse, nlmixr2
Encoding: UTF-8
VignetteBuilder: knitr
Config/pak/sysreqs: libicu-dev
Repository: https://insightrx.r-universe.dev
Date/Publication: 2026-06-25 13:48:34 UTC
RemoteUrl: https://github.com/insightrx/pkpdsim
RemoteRef: HEAD
RemoteSha: c8a0ef51242071f6677a27681b700a0286cc2ae2
NeedsCompilation: yes
Packaged: 2026-06-25 14:34:11 UTC; root
Author: Ron Keizer [aut, cre],
  Jasmine Hughes [aut],
  Dominic Tong [aut],
  Kara Woo [aut],
  Jordan Brooks [aut],
  InsightRX [cph, fnd]
Maintainer: Ron Keizer <ron@insight-rx.com>